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Safety Considerations and Who Should Seek Provider Evaluation First Patients with pre-existing kidney disease, liver dysfunction, or history of pancreatitis should not begin either semaglutide or glutathione supplementation without thorough medical evaluation

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In addition, medication side effects like nausea, vomiting, and diarrhea can lead to fluid loss

Dietary factors : High sodium intake, excessive animal protein consumption, and low calcium intake can alter urinary composition and promote stone formation

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