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Overall, these findings show that GLP-1R recycling is influenced by persistence of agonist binding within the endosomal compartment, resulting in enhanced insulin-releasing properties of fast-dissociating agonists which maintain an adequate population of cell surface receptors over prolonged periods

Circ Arrhythm Electrophysiol 2018

[DOI] [PMC free article] [PubMed] [Google Scholar] 179.Perry T, et al